To fortify domestic supply chains, the Biden Administration has created the White House Council on Supply Chain Resilience and is actively advocating for the deployment of digital technologies, emphasizing the use of machine learning and artificial intelligence (AI). One of the goals of strengthening the U.S. supply chain is to increase the domestic manufacturing of medicines to lower costs for families and reduce risk. To do that, existing technology should be leveraged at a greater scale and the Administration should leverage private companies with a long history of logistics expertise.